S 2022, 11,ten ofFoods 2022, 11,impact on gastrointestinal mucosal regeneration with an inflammatory bowel disease (IBD) rat model. [40]. We found that Lentilactobacillus buchneri URN103L with -glucosidase activity, isolated in the fermentation of medicinal plants, has the prospective to convert ginsenoside Rb1 into Rd and Rg3. Within the future, we hope that various biological functions ten of 13 of ginsenosides, which include ginsenoside Rg3, might be revealed and play an important part in human well being.Figure 9. Ginsenoside conversion of ginseng root by Lentilactobacillus buchineri URN103L for fermenFigure 9. Panax ginseng root; (B) days; (C) days; (D) 14 days. tation: (A) Ginsenoside conversion 3of ginseng7root by Lentilactobacillus buchineri URN103L for fermentation: (A) Panax ginseng root; (B) 3 days; (C) 7 days; (D) 14 days.Ginsenoside Rg3, on the list of saponins in American ginseng (Panax quinquefolius L.(-)-Hydroxycitric acid Biological Activity Araliaceae), has been shown to inhibit tumor growth. Probably the most impacted pathway of antihuman colorectal cancer activity is definitely the Ephrin receptor pathway in HCT-116 human colorectal cancer cells [30]. In radiation therapy combined with surgery or chemotherapy, RgFoods 2022, 11,11 of4.Turkesterone supplier Conclusions Amongst the 17 varieties of LAB exhibiting constructive -glucosidase activity in the fermentation goods of Korean medicinal plants, only 1 isolate (i.e., URN103L) showed higher hydrolytic activity on ginsenoside Rb1. The LAB strain was identified as L. buchneri URN103L, which showed 99 homology with Lentilactobacillus buchneri NRRLB 30929. The optimum hydrolysis activity on the -glucosidase enzyme on saponins occurred at 35 C and pH 5.0. The identified strain URN103L showed larger -glucosidase activities than any other strain.PMID:24732841 This study confirms that the -glucosidase of L. buchneri URN103L isolated from Korean fermented medicinal plants can successfully convert ginsenoside Rb1 into Rd and Rg3. The converted ginsenoside is often employed inside the food, cosmetic, and also other overall health item industries.Author Contributions: Conceived and created the experiments: G.R., U.M., M.S.N. Performed the experiments: G.R., U.M., H.C.B. Analyzed the data: U.M., H.C.B. Wrote the paper: G.R., U.M., S.-H.C., M.S.N. All authors have study and agreed for the published version with the manuscript. Funding: This study received no external funding. Institutional Assessment Boarding Statement: Not applicable. Informed Consent Statement: Not applicable. Information Availability Statement: The datasets utilised and analyzed within this study are readily available in the corresponding author on reasonable request. Acknowledgments: This study was supported in 2021 by study funds in the Institute of Agricultural Science, College of Agriculture and Life Sciences, Chungnam National University (0682-01). Conflicts of Interest: The authors declare no conflict of interests.
acsami.orgResearch ArticleHyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage FormsShaquib Rahman Ansari, Nele-Johanna Hempel, Shno Asad, Peter Svedlindh, Christel A. S. Bergstr , Korbinian L mann, and Alexandra TelekiCite This: ACS Appl. Mater. Interfaces 2022, 14, 21978-21988 Study Onlinesi Supporting InformationACCESSMetrics MoreArticle RecommendationsABSTRACT: Superparamagnetic iron oxide nanoparticles (SPIONs) create heat upon exposure to an alternating magnetic field (AMF), which has been studied for hyperthermia treatment and triggered drug release. This study introduces a novel application of magne.
