Product Name :
Lavoltidine
Description:
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.
CAS:
76956-02-0
Molecular Weight:
359.47
Formula:
C19H29N5O2
Chemical Name:
1-methyl-5-[(3-3-[(piperidin-1-yl)methyl]phenoxypropyl)amino]-1H-1,2,4-triazol-3-ylmethanol
Smiles :
CN1N=C(CO)N=C1NCCCOC1C=C(CN2CCCCC2)C=CC=1
InChiKey:
VTLNPNNUIJHJQB-UHFFFAOYSA-N
InChi :
InChI=1S/C19H29N5O2/c1-23-19(21-18(15-25)22-23)20-9-6-12-26-17-8-5-7-16(13-17)14-24-10-3-2-4-11-24/h5,7-8,13,25H,2-4,6,9-12,14-15H2,1H3,(H,20,21,22)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Mitoxantrone supplier
Additional information:
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist.Fenretinide Epigenetics Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.PMID:32644756 |Product information|CAS Number: 76956-02-0|Molecular Weight: 359.47|Formula: C19H29N5O2|Chemical Name: 1-methyl-5-[(3-3-[(piperidin-1-yl)methyl]phenoxypropyl)amino]-1H-1,2,4-triazol-3-ylmethanol|Smiles: CN1N=C(CO)N=C1NCCCOC1C=C(CN2CCCCC2)C=CC=1|InChiKey: VTLNPNNUIJHJQB-UHFFFAOYSA-N|InChi: InChI=1S/C19H29N5O2/c1-23-19(21-18(15-25)22-23)20-9-6-12-26-17-8-5-7-16(13-17)14-24-10-3-2-4-11-24/h5,7-8,13,25H,2-4,6,9-12,14-15H2,1H3,(H,20,21,22)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice.|Products are for research use only. Not for human use.|
