PF-06651600 is a Orally Active and Covalent JAK3-Selective Inhibitor
|JAK/STAT-dependent cytokines are essential for the development, proliferation, and function of T-cells. The JAK...
BRD5529 is a Selective CARD9–TRIM62 PPI Inhibitor
|The allele family CARD9 variant relates to increased or protected risk of inflammatory bowel...
ACT-389949 is a Selective FPR2/ALX Agonist
|Neutrophil granulocytes play an important role in regulating and fine-tuning inflammatory reactions. FPRs can...
MS4078 Inhibits an Immune Response Target NPM-ALK Protein
|Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase. ALK belongs to the insulin...
ACHN-975 is a First-in-class and Selective LpxC Inhibitor
|The bacterial enzyme UDP-3-O--N-acetylglucosamine deacetylase (LpxC) catalyzes the first committed step of lipid A...